Week 6 of the NFL 2025 season brings an exciting lineup of games. Florio and Simms have made their predictions for this week’s matchups, showcasing their unique insights and contrasting opinions. After a challenging previous week, both analysts are eager to improve their records.
NFL Week 6 Matchups and Predictions
Florio had a disappointing week, going 4-10 straight up and 6-8 against the spread. His overall season record stands at 51-26-1 for straight-up picks and 44-34 against the spread. Meanwhile, Simms performed better, holding records of 49-28-1 and 39-39 respectively. This week, the analysts disagree on only one game.
Key Matchups for Week 6
- Eagles (-7) at Giants
- Florio’s prediction: Eagles 24, Giants 13
- Simms’s prediction: Eagles 27, Giants 17
- Broncos (-7.5) vs. Jets (in London)
- Florio’s prediction: Broncos 28, Jets 9
- Simms’s prediction: Broncos 28, Jets 13
- Rams (-7.5) at Ravens
- Florio’s prediction: Rams 30, Ravens 13
- Simms’s prediction: Rams 34, Ravens 17
- Cowboys (-3) at Panthers
- Florio’s prediction: Cowboys 27, Panthers 20
- Simms’s prediction: Cowboys 31, Panthers 27
- Colts (-7) vs. Cardinals
- Florio’s prediction: Colts 27, Cardinals 17
- Simms’s prediction: Colts 31, Cardinals 20
- Seahawks at Jaguars (-1.5)
- Florio’s prediction: Jaguars 21, Seahawks 17
- Simms’s prediction: Jaguars 34, Seahawks 24
- Chargers (-4.5) at Dolphins
- Florio’s prediction: Chargers 27, Dolphins 24
- Simms’s prediction: Chargers 23, Dolphins 20
- Patriots (-3.5) at Saints
- Florio’s prediction: Patriots 24, Saints 16
- Simms’s prediction: Patriots 28, Saints 17
- Browns at Steelers (-5.5)
- Florio’s prediction: Steelers 24, Browns 14
- Simms’s prediction: Steelers 20, Browns 13
- Titans at Raiders (-3.5)
- Florio’s prediction: Raiders 28, Titans 24
- Simms’s prediction: Raiders 20, Titans 13
- Bengals at Packers (-14)
- Florio’s prediction: Packers 34, Bengals 17
- Simms’s prediction: Packers 35, Bengals 20
- 49ers at Buccaneers (-3)
- Florio’s prediction: Buccaneers 31, 49ers 27
- Simms’s prediction: Buccaneers 24, 49ers 20
- Lions at Chiefs (-2.5)
- Florio’s prediction: Lions 30, Chiefs 24
- Simms’s prediction: Lions 30, Chiefs 21
- Bills (-4.5) at Falcons
- Florio’s prediction: Bills 23, Falcons 20
- Simms’s prediction: Bills 24, Falcons 21
- Bears at Commanders (-4.5)
- Florio’s prediction: Commanders 35, Bears 27
- Simms’s prediction: Bears 34, Commanders 31
Conclusion
As Week 6 unfolds, fans will look to see if Florio can regain his footing against Simms. With challenging matchups ahead, betting responsibly is essential. Tune in to El-Balad for continued coverage and analysis of the NFL 2025 season.
