India’s Weight-Loss Drug Surge: Risks of Rybelsus, Mounjaro, and Wegovy

India’s burgeoning anti-obesity drug market has witnessed a remarkable transformation, soaring sixfold within five years. The increasing demand for weight-loss medications has sparked numerous inquiries from young professionals eager to combat weight gain attributed to demanding lifestyles.
Growing Popularity of Weight-Loss Drugs
Many young individuals, including a 23-year-old man, are seeking these drugs. Patients frequently ask doctors about starting weight-loss medications, often influenced by peers who are already using injectable treatments to shed excess pounds. However, experts caution that while these drugs may offer quick results, they are not substitutes for a balanced diet or an active lifestyle.
Types of Weight-Loss Drugs
The primary medications in India’s weight-loss arena include:
- Semaglutide: Marketed as Rybelsus (oral) and Wegovy (injectable) by Novo Nordisk.
- Tirzepatide: Marketed as Mounjaro by Eli Lilly, primarily for diabetes but increasingly used for weight loss.
Both drugs mimic a natural hormone that regulates appetite, leading to a faster feeling of fullness. They are administered once a week through easy-to-use injectors.
Risks and Side Effects
Despite their effectiveness, GLP-1 drugs come with potential risks. Users may regain lost weight within a year of discontinuation, and prolonged use without exercise could result in muscle loss. Common side effects include:
- Nausea
- Diarrhea
- Gallstones
- Pancreatitis
The risks are compounded by India’s dietary patterns, which often enhance the likelihood of sarcopenic obesity.
Market Growth and Future Trends
India’s anti-obesity drug market has skyrocketed from $16 million in 2021 to nearly $100 million today, as reported by Pharmarack. Novo Nordisk primarily leads this surge, with Rybelsus capturing a significant share. Predictions indicate that following the expiration of semaglutide’s patent in early 2024, the market could witness an influx of generics, potentially reaching $1 billion.
However, this surge in affordability brings concerns regarding misuse. Instances of individuals obtaining high doses from non-medical professionals such as trainers and dieticians have emerged, alongside the circulation of counterfeit medications in the market. Experts urge caution as the introduction of generics could exacerbate these problems.
Changing Perceptions of Obesity
In India, the social perception of obesity complicates the approach to treatment. Many people incorrectly view obesity as a sign of affluence, leading to a reluctance to acknowledge its seriousness. Health professionals advocate for a shift in understanding, framing obesity as a chronic disease rather than merely a lifestyle issue.
As societal attitudes toward obesity evolve, various medical specialties are beginning to utilize weight-loss drugs to improve health outcomes beyond mere aesthetics. These include endocrinologists, cardiologists, and orthopedic surgeons, who prescribe them to help manage conditions such as sleep apnea, which can significantly affect quality of life.
Conclusion
The emergence of new weight-loss drugs in India marks a significant shift in tackling obesity. While they promise results, the underlying health risks, potential for misuse, and the necessity of lifestyle changes remain crucial topics for discussion. Health professionals advocate using these drugs responsibly to address serious health concerns rather than superficial weight loss goals.



