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Top Fantasy Football Players to Start in Week 6, 2025

The 2025 Fantasy Football season is heating up as Week 6 approaches, posing challenges for many managers. With teams like the Minnesota Vikings and Houston Texans on bye, significant players such as Justin Jefferson and Nico Collins will be unavailable. This situation creates a need for optimal lineup decisions. Here’s a look at the top fantasy football players to start in Week 6.
Key Players to Start in Week 6
- Jaxon Smith-Njigba (WR, Seattle Seahawks): Smith-Njigba has been performing at a high level, making him a strong start against the Jacksonville Jaguars, who rank 23rd in yards allowed.
- Sam Darnold (QB, Seattle Seahawks): Darnold continues to be a viable streaming option for fantasy. Expect solid contributions against a struggling Jaguars’ defense.
- AJ Barner (TE): Don’t overlook Barner as a breakout tight end this season. He could be a valuable addition if available on waivers.
Top Running Backs to Consider
- Rico Dowdle: With Chuba Hubbard sidelined, Dowdle emerged as an outstanding replacement last week, rushing for 206 yards and a touchdown. He faces his former team, the Dallas Cowboys, who rank 28th in Fantasy Points Per Game against running backs.
- Tony Pollard: Pollard is set to benefit as the Tennessee Titans face the Las Vegas Raiders. The Raiders have allowed the second-most rushing touchdowns to running backs this season.
- Rhamondre Stevenson: With the Patriots losing Antonio Gibson for the season, Stevenson will continue to play a crucial role. He scored two touchdowns last week and remains an essential part of the offense against the New Orleans Saints.
- Kareem Hunt: A good streaming option this week, Hunt has found the end zone frequently, scoring three touchdowns in his last three games. Expect him to be involved in a high-scoring matchup against the Detroit Lions.
As fantasy players navigate Week 6, these players stand out due to their potential for strong performances. Consider your lineup carefully as injuries and bye weeks impact decisions. Each of these players offers viable options to maximize your scoring potential in fantasy football.