Thanksgiving Day Football: Predictions, Picks, and X Factors for All Games

The 2025 NFL Thanksgiving Day games promise thrilling matchups in Week 13, featuring three key contests. With an average over/under total of 51.2 points, this year is set to see the highest scoring anticipated on this holiday in 40 seasons.
Key Thanksgiving Day Matchups
Green Bay Packers vs. Detroit Lions
- Date & Time: November 26, 2025, 1 p.m. ET
- Network: Fox
- Betting Line: Lions favored by 2.5 points (O/U: 48.5)
The Packers enter as underdogs for the first time this season. Previously, they were favored in all their games leading to Week 13. They have shown improvement, winning two division games compared to last season’s defeats against the Lions and Vikings.
The Lions seek to avenge their earlier loss to the Packers this season, a 27-13 setback at Lambeau Field. Head Coach Dan Campbell emphasizes the significance of this rivalry, given that Detroit leads their historical matchups. Defensive performance will be crucial; the Packers’ defense generates pressure 35% of the time, which could pose problems for Lions quarterback Jared Goff.
Kansas City Chiefs vs. Dallas Cowboys
- Date & Time: November 26, 2025, 4:30 p.m. ET
- Network: CBS
- Betting Line: Chiefs favored by 3 points (O/U: 52.5)
The Chiefs look to build on their recent comeback victory over the Colts, where quarterback Patrick Mahomes expressed the need to maintain momentum. On the other hand, the Cowboys’ defense has been performing well, recently shutting down several high-scoring offenses.
Mahomes will face a significant challenge against the Cowboys’ defensive strategies, while Dak Prescott thrives under play-action, a feeble point for the Chiefs’ defense this year. Expect a high-scoring affair as both teams are determined to improve their playoff standings.
Cincinnati Bengals vs. Baltimore Ravens
- Date & Time: November 26, 2025, 8:20 p.m. ET
- Network: NBC
- Betting Line: Ravens favored by 7 points (O/U: 52.5)
The Bengals emphasize the importance of turnovers in divisional games, needing a solid defensive performance against the Ravens. Running back Derrick Henry is on the verge of breaking Jim Brown’s rushing touchdown record. The Bengals rank poorly in rushing defense, which could be exploited by the Ravens’ offense.
With the potential for a high-scoring game, Lamar Jackson’s passing ability against a struggling Bengals defense could lead to a decisive match-up for the Ravens.
Thanksgiving Game Memories
Each team has its unique Thanksgiving memories. The Packers pulled off a stunning upset against the Lions in 2023, while the Lions celebrated their first Thanksgiving win under Coach Campbell in 2024. The Chiefs’ historic moment came when Marcus Allen surpassed Walter Payton’s rushing touchdown record in 1996, and the Cowboys recall Clint Longley’s dramatic win in 1974.
This Thanksgiving, fans can expect high-stakes football, filled with passionate rivalries and historical significance. As teams vie for playoff positions, these matchups will not only entertain but also possibly reshape the landscape of the NFL season.



