NFL Fantasy 2025: Week 5 Running Backs to Start and Sit

As NFL Fantasy 2025 progresses, Week 5 presents significant considerations for running backs. Analyzing recent performances helps identify which players to start or sit for the upcoming matchups.
NFL Fantasy 2025: Week 5 Running Backs to Start
This week, certain running backs stand out due to favorable matchups and recent performances. Coaches must make critical decisions based on player statistics and defensive weaknesses.
Key Running Backs to Consider
- Antonio Gibson: Although he has had a fluctuating role, Gibson is receiving a solid amount of work.
- Darrell Henderson: In Week 4, Henderson outperformed Gibson in key metrics, recording more snaps and targets. He also scored a touchdown, signaling his upward trend.
Matchup Breakdown: Buffalo Defense
The Buffalo defense has struggled against running backs this season. They currently rank among the teams allowing the most rushing yards. This trend makes their matchup particularly appealing for fantasy managers.
Statistical Insights
- Buffalo’s defense concedes the eighth-most rushing yards per game.
- They have the highest rate of explosive runs allowed in the NFL.
Strategic Decisions for Fantasy Owners
Due to these factors, both Gibson and Henderson are viable options this week. While Stevenson remains the primary rusher, his average of 10.5 touches per game makes him a flex play as well.
Take advantage of these insights to optimize your fantasy lineup. The potential for explosive plays and favorable matchups sets the stage for an exciting Week 5 in NFL Fantasy.